Chronic Opioid Use Side Effects

Up to 80 of patients taking opioids experience at least one side effect. In addition to the risk of developing opioid use disorder oud long term opioid use has been shown to cause chronic inflammation and hyperalgesia suggesting that opioids may induce an immune. Common side effects of opioid administration include sedation dizziness nausea vomiting constipation physical dependence tolerance and respiratory depression.

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Constipation nausea and dyspepsia are the most common long term adverse effects of chronic opioid use strength of recommendation sor.

Chronic opioid use side effects.

The most common being gastrointestinal problems like constipation nausea and vomiting. Other long term effects of opioid use include. Hypersensitivity to pain caused by opioid use which causes the nervous system to become overly sensitive. A disorder also known as delayed gastric emptying which slows or stops the movement of food from the.

B systematic review of low quality studies. Central nervous system side effects are also common like impaired concentration confusion sleep and memory problems. Addiction irregular heart beat increased risk of heart attack depression constipation severe abdominal pain hormonal problems weak bones increased pain. Physical dependence and addiction are clinical concerns that may prevent proper prescribing and in turn inadequate pain management.

Less common side effects of opioid use may include. Men may experience depression fatigue and sexual dysfunction sor. B 2 observational studies.